发明名称 LIQUID FORMULATION COMPRISING GM-CSF NEUTRALIZING COMPOUND.
摘要 The present invention relates to aqueous formulations comprising a compound neutralizing GM-CSF in concentrations of at least about 20 mg/ml, a tonicity modifier and a buffer, wherein the composition is stable. The ingredients of the formulation preferably provide stability to the compound neutralizing GM-CSF in view of long-term storage. In a preferred aspect, the formulation is for use in therapy, preferably for use in the treatment of inflammatory and autoimmune disorders, preferably including allergic and psoriatic disorders, as well as arthritic and asthmatic disorders. Furthermore, a kit comprising the formulation of the invention is provided.
申请公布号 MX2015005237(A) 申请公布日期 2015.10.29
申请号 MX20150005237 申请日期 2013.10.31
申请人 AMGEN RESEARCH (MUNICH) GMBH 发明人 THOMAS URBIG;THOMAS BOEHM;MICHAEL MOLHOJ;WOLFRAM STEINHILBER
分类号 A61K39/395;C07K16/24 主分类号 A61K39/395
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