Formation of n-protected bis-3,6-(4-aminobutyl)-2,5-diketopiperazine through a cyclic alpha-n-protected amino ester
摘要
A method for the synthesis of N-protected 3,6-aminoalkyl-2,5-diketopiperazines is provided. The method includes obtaining a cyclic α-N protected active amino ester and adding it to a mixture of an amine catalyst in an organic solvent.