| 发明名称 |
Compositions for Delivering Drugs with Low Water Solubility |
| 摘要 |
The present invention provides compositions comprising polymeric micelles containing a drug with low water solubility, wherein sterol rings of pegylated sterols and the drug form a hydrophobic portion and polyethylene glycol chains of the pegylated sterols forms a hydrophilic portion. The present invention also provides methods of preparing and using such compositions for delivering drug(s) with low water solubility to a subject in need thereof. |
| 申请公布号 |
US2015306225(A1) |
申请公布日期 |
2015.10.29 |
| 申请号 |
US201514662313 |
申请日期 |
2015.03.19 |
| 申请人 |
Juntech Pharmaceuticals L.L.C. |
发明人 |
Yang Jun |
| 分类号 |
A61K47/28;A61K9/107;A61K31/436;A61K31/517;A61K31/7048;A61K31/337;A61K38/13 |
主分类号 |
A61K47/28 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A composition comprising polymeric micelles containing a drug with low water solubility, wherein said polymeric micelles comprise a hydrophobic portion formed by sterol rings of pegylated sterols and the drug; and a hydrophilic portion formed by polyethylene glycol chains of the pegylated sterols. |
| 地址 |
Ballwin MO US |
