| 发明名称 |
TRANS-4--N,N-DIMETHYLCARBAMOYL-CYCLOHEXYLAMINE FOR TREATING NEGATIVE SYMPTOMS OF SCHIZOPHRENIA |
| 摘要 |
The present invention relates to trans-4-{2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cyclohexylamine (cariprazine) and pharmaceutically acceptable salts and hydrates and solvates and polymorphs thereof for use in the treatment of primary negative symptoms of schizophrenia and/or predominantly negative symptoms of schizophrenia. |
| 申请公布号 |
US2015306094(A1) |
申请公布日期 |
2015.10.29 |
| 申请号 |
US201314646226 |
申请日期 |
2013.11.28 |
| 申请人 |
RICHTER GEDEON NYRT. |
发明人 |
Pitter János György;Szatmári Balázs;Debelle Marc;Németh György József;Laszlovszky István |
| 分类号 |
A61K31/495 |
主分类号 |
A61K31/495 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method of treating one or more primary negative symptoms of schizophrenia, the method comprising administering to a patient in need thereof a therapeutically effective amount of trans-4-{2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cyclohexylamine, or a pharmaceutically acceptable salt, hydrate, solvate, or polymorph thereof. |
| 地址 |
Budapest HU |
