发明名称 |
STABILIZATION OF CYTOCHROME P450 REDUCTASE |
摘要 |
The present invention relates to a recombinant microorganism which is capable of expressing a cytochrome P450 reductase (CPR) and, optionally, a cytochrome P450 enzyme (CYP) and which is capable of overexpressing a Ice2p comprising the amino acid sequence set out in SEQ ID NO: 2 or a sequence having at least 50% sequence identity thereto. The invention further relates to use of Ice2p to stabilize expression of a cytochrome P450 reductase in a recombinant microorganism. |
申请公布号 |
WO2015162305(A1) |
申请公布日期 |
2015.10.29 |
申请号 |
WO2015EP59225 |
申请日期 |
2015.04.28 |
申请人 |
DSM IP ASSETS B.V. |
发明人 |
EMMERSTORFER, ANITA;WRIESSNEGGER, TAMARA;WIMMER-TEUBENBACHER, MIRIAM;PICHLER, HARALD;MUELLER, MONIKA;KALUNZA, IWONA;SCHURMANN, MARTIN |
分类号 |
C12N9/02;C07K14/395;C12P7/26;C12P19/56;C12P33/00 |
主分类号 |
C12N9/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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