发明名称 |
APPLICATION OF INDUCED PLURIPOTENT STEM CELLS TO GENERATE ADOPTIVE CELL THERAPY PRODUCTS |
摘要 |
The application of induced pluripotent stem cells (iPSCs) to generate adoptive cell therapy products and usage of iPSCs for screening potential toxicity of immune receptors are described herein. In some aspects, iPSCs and cells differentiated therefrom are provide which do not express a HLA gene (e.g., HLA-A). |
申请公布号 |
CA2945393(A1) |
申请公布日期 |
2015.10.29 |
申请号 |
CA20152945393 |
申请日期 |
2015.04.24 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
COOPER, LAURENCE J.N.;TORIKAI, HIROKI |
分类号 |
C12N5/071;C12N5/0735;C12N5/0789;C12N5/10;C12N9/22;C12N15/00;C12N15/55;C12N15/86;C12Q1/00;C40B40/02 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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