| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide a technique for increasing thermal stability of dibutylhydroxytoluene and inhibiting a temporal decrease of its content in a liquid drug containing dibutylhydroxytoluene and pranoprofen and/or a salt thereof.SOLUTION: Thermal stability of dibutylhydroxytoluene in a liquid drug can be increased, as well as adsorption of dibutylhydroxytoluene to a container can be inhibited and thereby the temporal decrease of its content can be inhibited by compounding organic amine with a hydroxyl group, citric acid, and/or a pharmaceutically acceptable salt of citric acid into a liquid drug containing dibutylhydroxytoluene and pranoprofen and/or a salt thereof, and employing a resin containing polybutylene terephthalate as the resin constituting a surface of an inner wall (a wall surface of an interior space in an expulsion section and/or a wall surface of a lid which faces an expulsion outlet of the expulsion section, or the like) of the container.</p> |
