发明名称 |
CANCER TREATMENT |
摘要 |
Diagnostic methods for predicting whether a human tumor is sensitive to treatment with axitinib, and methods of treating a human tumor are disclosed. The methods are based on measurement of CD68 polypeptide expression levels in a tissue sample from a tumor. CD68 expression levels can be measured using immunohistochemistry, where the percentage of CD68-positive cells and density of CD68-positive cells within the tumor can be determined. |
申请公布号 |
CA2946362(A1) |
申请公布日期 |
2015.10.29 |
申请号 |
CA20152946362 |
申请日期 |
2015.04.16 |
申请人 |
PFIZER INC. |
发明人 |
MARTINI, JEAN-FRANCOIS ANDRE;TARAZI, JAMAL CHRISTO;WILLIAMS, JAMES ANDREW |
分类号 |
G01N33/48;A61K31/4439;A61P35/00;G01N33/574 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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