METHOD FOR OBTAINING POROUS HOLLOW FIBERS HAVING MOLECULARLY IMPRINTED SPHERES EMBEDDED THEREIN AND MODULAR DEVICE FORMED BY THE RESULTING FIBERS

摘要

The invention relates to a method for obtaining porous hollow fibers having molecularly imprinted spheres embedded therein, said method comprising the steps of: simultaneously and independently injecting a doping solution and a pore-forming solution into an extrusion die; extruding or spinning porous hollow fibers; coagulating the porous hollow fibers that leave step (b) in an aqueous solution with an aqueous solution having a temperature between 15° C.-25° C.; winding the flexible porous hollow fibers coagulated in step (c); leaving them to dry and storing same under vacuum conditions. The resulting porous hollow fibers are used to form filtrating modules in which a plurality of fibers are disposed longitudinally and in parallel. The filtrating modules can be assembled together to form filtering devices intended, in a preferred example, for gradual blood purification and the subsequent qualitative and/or quantitative identification of the molecules retained in the first filter of each filtering module. The invention also relates to the operating method of the filtering device.

主权项

1. A process for obtaining porous hollow fibers with molecularly imprinted spheres embedded therein, characterized by comprising the steps of:
a) injecting (1) simultaneously and independently a doping solution and a pore-forming solution in an extrusion die; b) extruding or spinning hollow porous fibers; c) coagulating the hollow porous fibers in a aqueous solution coming from step b, with a aqueous solution that is at a temperature in the range of 15° C.-25° C.; d) coiling the flexible and hollow porous fibers coagulated in step c), let them dry and store in vacuum conditions.