| 发明名称 |
Aspartate-ß-hydroxylase Induces Epitope-specific T Cell Responses in Tumors |
| 摘要 |
The present invention provides a peptide-based immunotherapy for ASPH-expressing tumors. |
| 申请公布号 |
US2015306198(A1) |
申请公布日期 |
2015.10.29 |
| 申请号 |
US201514696207 |
申请日期 |
2015.04.24 |
| 申请人 |
RHODE ISLAND HOSPITAL |
发明人 |
Wands Jack R. |
| 分类号 |
A61K39/00;A61B17/12;C12N9/02 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising a therapeutically effective amount of a purified aspartate-β-hydroxylase (ASPH) peptide, wherein said peptide comprises at least 7 amino acids in length and fewer amino acids than the full length ASPH protein and wherein said peptide comprises an HLA class I or class II-restricted epitope sequence. |
| 地址 |
PROVIDENCE RI US |
