A GENETIC TEST TO PREDICT PATIENT RESPONSE TO BONE MORPHOGENETIC PROTEIN IN ARTHRODESIS

摘要

The present invention provides a method of predicting an increased likelihood of a complication associated with administration of a bone morphogenetic protein (BMP) to a subject in need of a spinal fusion surgery by detecting single nucleotide polymorphisms (SNPs) in the subject. Also provided are methods of treatment with a BMP based on the presence or absence of SNPs and kits for use in detecting the SNPs.