Sample Interval Modulation Magnetic Resonance Elastography

摘要

The invention disclosed herein provides methods for implementing Sampling Interval Modulation Magnetic Resonance Elastography (“SLIM-MRE”), based on simultaneous encoding and acquisition of individual displacement components using motion encoding gradients with different time discretization intervals to MRI analysis. The components are modulated with different frequencies in the MR signal phase, which can be expressed as a harmonic function of the start time, or equivalently of initial phase, of the motion encoding gradient components. As a result, all displacement components can be acquired faster than in conventional MRE, and can be derived from the same temporally-resolved MR phase images. This also allows for simultaneously acquired 3D displacement data and storage of such data in the same k-space.

主权项

1. In a magnetic resonance imaging (MRI) system, a computer-implemented method comprising:
while inducing a mechanical vibration in an object in the MRI system, applying a magnetic resonance (MR) signal to the object, the MR signal having a phase; encoding vibrational motion of the object in the MR signal phase simultaneously in three spatial dimensions by applying a motion encoding gradient (MEG) to the object simultaneously in the three spatial dimensions; and simultaneously acquiring in all three of the spatial dimensions magnetic resonance elastography (MRE) data including the MR signal phase encoded with the vibrational motion of the object in the three spatial dimensions.