Crystalline forms of (6R) -L-erythro-tetrahydrobiopterin dihydrochloride

摘要

C:/NRPorbl/DCC/MDT/4059582_ DOC-19/12/2011 CRYSTALLINE FORMS OF (6R)-L-ERYTHRO-TETRAHYDROBIOPTERIN DIHYDROCHLORIDE Abstract Crystal forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride, hydrates and solvates 5 and processes for their preparation are provided. These crystal forms are either intermedi-ates for the preparation of stable polymorphic form B or are suitable for solid formulations.