Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates

摘要

4-Amino-5-fluoro-3-halo-6-(substituted)picolinates are conveniently prepared from 4,5,6-trichloropicolinates by a series of steps involving fluorine exchange, amination, halogen exchange, halogenation and transition metal assisted coupling.