MODIFIED G-QUADRUPLEX NANOPARTICLES

摘要

This invention relates to a nucleic acid nanoparticle comprising at least one G-quadruplex structure wherein at least one guanine base comprises a modification in the N2-position and the use of said nucleic acid nanoparticle as a medicament, molecular sensor, or tag. Further this invention relates to methods of stabilizing a nucleic acid nanoparticle comprising at least one G-quadruplex structure.