Methods for Making Water Soluble Quantum Dots

摘要

A novel quantum dot containing two different metals at non-toxic levels which is capable of narrow bandwidth near infrared emissions at wavelengths of 600-1100 nm. The quantum dot is fabricated via an aqueous method which forms a structure having an inner region of one composition and an outer region of a different composition, wherein the inner region contains at least a first metal and the outer region contains at least a second metal. The quantum dots may be enabled for bioconjugation and may be used in a method for tissue imaging and analyte detection.

主权项

1. A quantum dot comprising:
an inner region comprising at least a first metal sulfide, selenide or sulfide selenide, and an outer region having a different composition than the inner region, said outer region comprising a second metal sulfide, selenide or sulfide selenide, and a cap, said quantum dot having at least one narrow bandwidth emission in the wavelength range from of about 600 nm to about 1100 nm.