p16INK4a derived peptides for prophylaxis and therapy of HPV-associated tumors and other p16INK4a expressing tumors

摘要

Described are particular fragments of the cyclin-dependent kinase inhibitor p16 capable of increasing IFN-³ secretion of T cells or inducing proliferation of T cells and the use of said fragments for immunizing an individual against HPV-associated or other p16 INK4a expressing carcinomas, preferably advanced carcinomas.