发明名称 SYK又はJAKキナーゼ阻害剤としての2,6−ジアミノ−ピリミジン−5−イル−カルボキサミド類
摘要 <p>The present invention is directed to compounds of formula I-V and tattooers thereof or pharmaceutically acceptable salts, esters, and pro drugs thereof which are inhibitors of sky kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.</p>
申请公布号 JP5802127(B2) 申请公布日期 2015.10.28
申请号 JP20110505030 申请日期 2009.04.16
申请人 发明人
分类号 C07D403/12;A61K31/506;A61K31/5377;A61K31/541;A61P3/10;A61P7/00;A61P7/02;A61P7/04;A61P7/06;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P25/00;A61P29/00;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D401/12;C07D401/14;C07D403/14;C07D405/12;C07D405/14;C07D409/12;C07D413/12;C07D417/12;C07D471/04;C07D487/04 主分类号 C07D403/12
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