发明名称 |
COMPOUNDS AND METHODS FOR THE ENRICHMENT OF MUTATED NUCLEIC ACID FROM A MIXTURE |
摘要 |
<p>The detection of the presence of rare somatic mutations from a biological sample is often challenging due to the simultaneous presence of a vast excess of wild-type DNA. The present invention describes novel compounds and methods that would allow the enrichment of mutant DNA by depleting amplifiable wild-type DNA.</p> |
申请公布号 |
EP2935619(A1) |
申请公布日期 |
2015.10.28 |
申请号 |
EP20130814889 |
申请日期 |
2013.12.19 |
申请人 |
ROCHE DIAGNOSTICS GMBH;F.HOFFMANN-LA ROCHE AG |
发明人 |
GUPTA, AMAR;SCHOENBRUNNER, NANCY |
分类号 |
C12Q1/68;C07F15/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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