| 发明名称 | Antibody to N-terminal region of hemoglobin β-chain | ||
| 摘要 | Provided is a general-purpose technique capable of measuring the HbA1c content, which is comparable to the IFCC reference method. An antibody which reacts with a peptide or a protein having an amino acid sequence of VHLTPE (SEQ ID NO: 1) at the N-terminus in which the N-terminal valine is not modified, but does not react with a peptide or a protein in which the N-terminal valine of the relevant polypeptide or protein is modified. | ||
| 申请公布号 | US9169320(B2) | 申请公布日期 | 2015.10.27 |
| 申请号 | US200913139201 | 申请日期 | 2009.12.10 |
| 申请人 | SEKISUI MEDICAL CO., LTD. | 发明人 | Miyazaki Osamu;Takubo Kohei;Kurashita Syunsuke |
| 分类号 | C07K16/18;C12N5/20;G01N33/531;G01N33/72;C12N5/16;C07K14/805 | 主分类号 | C07K16/18 |
| 代理机构 | Oblon, McClelland, Maier & Neustadt, L.L.P. | 代理人 | Oblon, McClelland, Maier & Neustadt, L.L.P. |
| 主权项 | 1. An antibody which specifically binds with a peptide or a protein comprising the amino acid sequence of VHLTPE (SEQ ID NO: 1) at the N-terminus in which the N-terminal valine is not modified, but does not specifically bind with a peptide or a protein comprising the amino acid sequence of VHLTPE (SEQ ID NO: 1) at the N-terminus in which the N-terminal valine is modified with a sugar, wherein the antibody is produced by a hybridoma selected from the group consisting of 85201, deposited as FERM BP-11187, 85202, deposited as FERM BP-11188, 85203, deposited as FERM BP-11189, 85204, deposited as, and 85206, deposited as FERM BP-11191. | ||
| 地址 | Tokyo JP | ||