| 发明名称 | Glucagon analogues | ||
| 摘要 | The invention provides materials and methods for promoting weight loss or preventing weight gain and for treating diabetes and associated metabolic disorders. In particular, the invention provides novel glucagon analogue peptide compounds effective in such methods. The compounds may mediate their effect by having, for example, increased selectivity for the GLP-1 receptor compared to human glucagon. | ||
| 申请公布号 | US9169310(B2) | 申请公布日期 | 2015.10.27 |
| 申请号 | US201113704299 | 申请日期 | 2011.06.24 |
| 申请人 | Zealand Pharma A/S | 发明人 | Riber Ditte;Meier Eddi |
| 分类号 | A61K38/26;A61K45/06;C07K14/605 | 主分类号 | A61K38/26 |
| 代理机构 | Clark & Elbing LLP | 代理人 | Clark & Elbing LLP ;Bieker-Brady Kristina |
| 主权项 | 1. A compound having the formula: R1—Z—R2,or a pharmaceutically acceptable salt thereof, wherein R1 is H, C1-4 alkyl, acetyl, formyl, benzoyl or trifluoroacetyl; R2 is OH or NH2; and Z is a peptide having the formula I: H-Aib-HGTFTSDYSKYLES-K(hexadecanoyl-isoGlu)-AAEEFVEWLLEA (SEQ ID NO:75). | ||
| 地址 | Glostrup DK | ||