| 发明名称 | Salt of fused heterocyclic derivative and crystal thereof | ||
| 摘要 | An objective of the present invention is to improve the solubility of 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyloxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid.;The present invention provides 3-[2-fluoro-5-(2,3-difluoro-6-methoxybenzyl-oxy)-4-methoxyphenyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,4-d]pyrimidine-5-carboxylic acid choline salt has excellent solubility and storage stability. | ||
| 申请公布号 | US9169266(B2) | 申请公布日期 | 2015.10.27 |
| 申请号 | US201113577832 | 申请日期 | 2011.02.09 |
| 申请人 | KISSEI PHARMACEUTICAL CO., LTD. | 发明人 | Jo Kazumichi;Takeuchi Hideki |
| 分类号 | C07D495/04;A61K31/519;A61P15/08;A61P15/16;A61P35/00;A61P15/18;A61P5/24 | 主分类号 | C07D495/04 |
| 代理机构 | Sughrue Mion, PLLC | 代理人 | Sughrue Mion, PLLC |
| 主权项 | 1. A compound represented by the formula: | ||
| 地址 | Matsumoto-shi JP | ||