| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: claimed group of inventions, which includes a pharmaceutical composition, a method of its obtaining, a drug form for per oral introduction with the claimed composition and a method of obtaining the drug form. The claimed invention is aimed at the pharmaceutical composition of a non-opiate analgesic/opiate analgesic, in which the non-opiate analgesic is contained in the core, opiate - in the first core coating, there is the second core coating with a water-insoluble polymer, as well as the second set of particles, containing the non-opiate analgesic and its coating with the water-insoluble polymer.EFFECT: flexibility of obtaining homogenous mixtures of non-opiate and opiate analgesics of different dosages of low-dose/high-dose medications without the necessity to produce separate particles of medicinal substances for different dosages, as well as a possibility to control the rate of medication release from the particles in different ways.26 cl, 4 dwg, 13 tbl, 8 ex |
