发明名称 |
Crystal forms of adefovir dipivoxil and processes for preparing the same |
摘要 |
The present invention relates to novel Forms A, B, C, D, E, F and G of crystalline 9-[2-[phosphonomethoxy]ethyl]adenine bis-pivaloyloxymethyl ester, i.e., adefovir dipivoxil, and processes for preparing them. According to the present invention, said novel crystal forms having a high purity can be obtained by a simple method and in a high yield. |
申请公布号 |
US9169257(B2) |
申请公布日期 |
2015.10.27 |
申请号 |
US201013256197 |
申请日期 |
2010.03.26 |
申请人 |
Daewoong Pharmaceutical Co., Ltd.;Daewoong Bio Inc. |
发明人 |
Choi Soo Jin;Lee Byung Goo;Oh Seong Soo;Kim Yong Tae;Kim Kwang Joo;Kim Hye Jin |
分类号 |
C07D473/34;C07F9/6561 |
主分类号 |
C07D473/34 |
代理机构 |
Troutman Sanders LLP |
代理人 |
Sullivan Clark G.;Troutman Sanders LLP |
主权项 |
1. Crystalline adefovir dipivoxil (Form B) comprising a powder XRD pattern having characteristic peaks (2θ) at 7.3, 16.3, 17.2, and 22.2 degrees. |
地址 |
Kyunggi-do KR |