发明名称 Crystal forms of adefovir dipivoxil and processes for preparing the same
摘要 The present invention relates to novel Forms A, B, C, D, E, F and G of crystalline 9-[2-[phosphonomethoxy]ethyl]adenine bis-pivaloyloxymethyl ester, i.e., adefovir dipivoxil, and processes for preparing them. According to the present invention, said novel crystal forms having a high purity can be obtained by a simple method and in a high yield.
申请公布号 US9169257(B2) 申请公布日期 2015.10.27
申请号 US201013256197 申请日期 2010.03.26
申请人 Daewoong Pharmaceutical Co., Ltd.;Daewoong Bio Inc. 发明人 Choi Soo Jin;Lee Byung Goo;Oh Seong Soo;Kim Yong Tae;Kim Kwang Joo;Kim Hye Jin
分类号 C07D473/34;C07F9/6561 主分类号 C07D473/34
代理机构 Troutman Sanders LLP 代理人 Sullivan Clark G.;Troutman Sanders LLP
主权项 1. Crystalline adefovir dipivoxil (Form B) comprising a powder XRD pattern having characteristic peaks (2θ) at 7.3, 16.3, 17.2, and 22.2 degrees.
地址 Kyunggi-do KR