发明名称 |
LPAR—substituted cyanopyrazole compounds |
摘要 |
Provided herein are compounds of the formula (I), as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of inflammatory diseases and disorders such pulmonary fibrosis.; |
申请公布号 |
US9169215(B2) |
申请公布日期 |
2015.10.27 |
申请号 |
US201314421094 |
申请日期 |
2013.09.02 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
Budd David;Qian Yimin;Schoenfeld Ryan Craig;Sidduri Achyutharao |
分类号 |
C07D231/38 |
主分类号 |
C07D231/38 |
代理机构 |
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代理人 |
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主权项 |
1. A compound of formula (I): wherein: R1 is lower alkyl or cycloalkyl; and R2 is phenyl, unsubstituted or mono-, bi- or tri-substituted independently with alkoxy, phenyl alkoxy, lower alkyl or halogen; naphthalenyl, unsubstituted or substituted with alkoxy; or indenyl, unsubstituted or substituted with alkoxy; or a pharmaceutically acceptable salt thereof. |
地址 |
Nutley NJ US |