发明名称 derivados de 5-(4-metanossulfonil-fenil)-tiazol para o tratamento de doenças agudas e inflamatórias crônicas.
摘要 The invention relates to the use of a compound of formula (I) or a pharmaceutically acceptable salt, prodrug and/or solvate thereof, in the preparation of a medicament for the treatment of an acute or chronic inflammatory disease, by inhibiting the production of at least one pro-inflammatory cytokine selected from TNF-alpha and IFN-gamma, or by inmunomodulating the IL-8 chemokine and/or the IL-10 regulatory cytokine. The invention also relates to novel compounds of formula (I') or a pharmaceutically acceptable salt, prodrug and/or solvate thereof, as well as a pharmaceutical composition comprising said compound.
申请公布号 BRPI0915325(A2) 申请公布日期 2015.10.27
申请号 BR2009PI15325 申请日期 2009.06.15
申请人 FAES FARMA, S.A. 发明人 ANA MUÑOZ MUÑOZ;ANTONIO DE LA HERA MARTÍNEZ;MELCHOR ÁLVAREZ DE MON SOTO;VICTOR RUBIO ROYO
分类号 C07D277/24;A61K31/425 主分类号 C07D277/24
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