发明名称 derivados de éter de pirrolidina como antagonistas do receptor de nk3
摘要 The present invention relates to compounds of formula I wherein R1, R2, R3, R′, Ar, m, n, and o are as defined herein. The invention also relates to pharmaceutical compositions containing compounds of formula I and methods for the manufacture of such compounds and compositions. Compounds of the invention are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).
申请公布号 BRPI0914797(A2) 申请公布日期 2015.10.27
申请号 BR2009PI14797 申请日期 2009.06.08
申请人 F. HOFFMANN-LA ROCHE AG 发明人 ANJA LIMBERG;CLAUS RIEMER;HASANE RATNI;HENNER KNUST;KENICHI KAWASAKI;MATTHIAS NETTEKOVEN;PHILIPPE JABLONSKI
分类号 A61K31/445;A61P25/00;C07D401/12;C07D401/14 主分类号 A61K31/445
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