Anti-obesity agent comprising compound containing benzotropolone ring

摘要

The object of the present invention is to provide an anti-obesity agent which contains a tea-derived component and which is safe and does not compromise the flavor of foods and beverages.;According to the present invention, a safe and palatable anti-obesity agent can be provided by incorporating a benzotropolone ring-containing compound which has tea-derived, high inhibitory activities against lipase and alfa-glucosidase. The anti-obesity agent of the present invention does not compromise the flavor of foods and beverage, has palatability, and can be used in various use applications including foods and beverages intended for health enhancement such as reduction in triglycerides.

主权项

1. A method of inhibiting lipase activity comprising: administering one or more compounds of Formula (1) to a subject in need thereof, wherein the compounds of Formula (1) are selected from: wherein R1 is H or OH; R2 is H or a group of Formula (2): wherein R4 is OH, a group of Formula (3): or a group of Formula (4): R3 is COOH, a group of Formula (5): or a group of Formula (6): wherein R5 is OH, a group of Formula (7): or a group of Formula (8): wherein R6 is a group of Formula (9): or a group of Formula (10): wherein R1′ is the same group as R1 above and R2′ is a group of Formula (11): wherein R4′ is the same group as R4 above,
excluding epitheaflagallin, epitheaflagallin-3-O-gallate, theaflavin, theaflavin-3-O-gallate, theaflavin-3′-O-gallate, and theaflavin-3,3′-O-digallate.