Profármacos de cianoguanidina

摘要

Un compuesto elegido entre el grupo que consiste en: cloruro de 1-[2-(2-(2-metoxietoxi)-etoxi)-etoxi-carboniloximetil]-4-[N'-ciano-N''-(6-(4-clorofenoxi)-hexil)-N-guanidino]- piridinio; cloruro de 1-[2-(2-metoxietoxi)-etoxi-carboniloximetil]-4-[N' 5 -ciano-N''-(6-(4-clorofenoxi)-hexil)-N-guanidino]-piridinio; cloruro de 1-[(2-metoxietoxi)-carboniloximetil]-4-[N'-ciano-N''-(6-(4-clorofenoxi)-hexil)-N-guanidino]-piridinio; yoduro de 1-[2-(2-(2-metoxietoxi)-etoxi)-etoxi-carboniloximetil]-4-[N'-ciano-N''-(6-(4-clorofenoxi)-hexil)-N-guanidino]- piridinio; N-[1-(2-(2-(2-metoxietoxi)-etoxi)-etoxicarboniloximetil)-1,4-dihidropiridin-4-ilideno]-N'-ciano-N''-(6-(4-clorofenoxi)- hexil)-guanidina; cloruro de 1-[2-(2-(2-metoxietoxi)-etoxi)-etoxi-carboniloximetil]-4-[N'-ciano-N''-(6-(4-clorofenoxi)-hexil)-N-guanidino]- piridinio; cloruro de 1-[1-(2-(2-metoxietoxi)-etoxi-carboniloxi)-etil]-4-[N'-ciano-N''-(6-(4-clorofenoxi)-hexil)-N-guanidino]-piridinio; cloruro de 1-[2-(2-(2-metoxietoxi)-etoxi)-etoxi-acetoximetil]-4-[N'-ciano-N''-(6-(4-clorofenoxi)-hexil)-N-guanidino]- piridinio; cloruro de 1-[2-(2-(2-(2-metoxietoxi)-etoxi)-etoxi)-etoxi-carboniloximetil]-4-[N'-ciano-N''-(6-(4-clorofenoxi)-hexil)-Nguanidino]- piridinio; cloruro de 1-[2-(2-(2-(2-(2-metoxietoxi)-etoxi)-etoxi)-etoxi)-etoxi-carboniloximetil]-4-[N'-ciano-N''-(6-(4-clorofenoxi)- hexil)-N-guanidino]-piridinio; cloruro de 1-[2-(2-(2-(2-(2-(2-metoxietoxi)-etoxi)-etoxi)-etoxi)-etoxi)-etoxi-carboniloximetil]-4-[N'-ciano-N''-(6-(4- clorofenoxi)-hexil)-N-guanidino]-piridinio; cloruro de 1-[2-(2-(2-metoxietoxi)-etoxi)-etoxi-carboniloximetil]-4-[N'-ciano-N''-(9-(dietoxifosfinoiloxi)-nonil)-Nguanidino]- piridinio; yoduro de 1-[2-(2-(2-metoxietoxi)-etoxi)-etoxi)-carboniloximetil]-4-[N'-ciano-N''-(12-(terc-butiloxicarbonilamino)- dodecil)-N-guanidino]-piridinio; cloruro de 1-[2-(2-(2-metoxietoxi)-etoxi)-etoxi)-carboniloximetil]-4-[N'-ciano-N''-(12-(terc-butiloxicarbonilamino)- dodecil)-N-guanidino]-piridinio; cloruro de 1-[2-(2-(2-(2-metoxietoxi)-etoxi)-etoxi)-etoxi-carboniloximetil]-4-[N'-ciano-N''-(12-(tercbutiloxicarbonilamino)- dodecil)-N-guanidino]-piridinio; yoduro de 1-[1-terc-butoxicarbonil)-4-piperidiloxi-carboniloximetil]-4-[N'-ciano-N''-(6-(4-clorofenoxi)-hexil)-Nguanidino]- piridinio; cloruro de 1-[4-piperidiloxi-carboniloximetil]-4-[N'-ciano-N''-(6-(4-clorofenoxi)-hexil)-N-guanidino]-piridinio, hidrocloruro; y N-[1-(α-(2-(2-(2-metoxietoxi)-etoxi)-etoxicarboniloxi)-bencil]-1,4-dihidropiridin-4-iliden]-N'-ciano-N''-(6-(4-clorofenoxi)- hexil)-guanidino.