| 摘要 |
The present invention addresses the problem of providing a method for preparing osteoblasts, said osteoblasts being applicable to repair of bone defects and treatments for bone resorption, bone fracture, osteoporosis, etc., with no canceration risk. As a means for solving the aforesaid problem, provided is a method for preparing osteoblasts, said method being characterized by comprising culturing differentiated mammalian somatic cells in a medium in the presence of at least one kind of compound selected from the group consisting of (1) a statin compound, (2) a casein kinase 1 inhibitor, (3) a cAMP inducer, and (4) a histone methyltransferase inhibitor to thereby convert the somatic cells into osteoblasts. |
