发明名称 TARGETED LIPOSOMAL FORM OF OLIGONUCLEOTIDE-POLYETHYLENEIMINE COMPLEX, ITS USE AND METHOD OF OBTAINING
摘要 The invention relates to the targeted, liposomal form of oligonucleotide-polyethyleneimine complex, characterized in that the oligonucleotide to polyethylenimine ratio ranges from 1:10 to 1:3, and the complex is encapsulated with a lipid bilayer enabling attachment of a targeting molecule recognizing the surface marker of pathological cells, as well as the method of obtaining the same and its application.
申请公布号 WO2015160270(A1) 申请公布日期 2015.10.22
申请号 WO2015PL50010 申请日期 2015.04.18
申请人 WROCŁAWSKIE CENTRUM BADAŃ EIT+ SP. Z O.O. 发明人 MEISSNER, JUSTYNA;TOPORKIEWICZ, MONIKA;KULICZKOWSKI, KAZIMIERZ;CZOGALLA, ALEKSANDER;SIKORSKI, ALEKSANDER
分类号 A61K47/48;A61K9/127;A61K48/00;A61P35/02;C12N15/88 主分类号 A61K47/48
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