发明名称 |
TARGETED LIPOSOMAL FORM OF OLIGONUCLEOTIDE-POLYETHYLENEIMINE COMPLEX, ITS USE AND METHOD OF OBTAINING |
摘要 |
The invention relates to the targeted, liposomal form of oligonucleotide-polyethyleneimine complex, characterized in that the oligonucleotide to polyethylenimine ratio ranges from 1:10 to 1:3, and the complex is encapsulated with a lipid bilayer enabling attachment of a targeting molecule recognizing the surface marker of pathological cells, as well as the method of obtaining the same and its application. |
申请公布号 |
WO2015160270(A1) |
申请公布日期 |
2015.10.22 |
申请号 |
WO2015PL50010 |
申请日期 |
2015.04.18 |
申请人 |
WROCŁAWSKIE CENTRUM BADAŃ EIT+ SP. Z O.O. |
发明人 |
MEISSNER, JUSTYNA;TOPORKIEWICZ, MONIKA;KULICZKOWSKI, KAZIMIERZ;CZOGALLA, ALEKSANDER;SIKORSKI, ALEKSANDER |
分类号 |
A61K47/48;A61K9/127;A61K48/00;A61P35/02;C12N15/88 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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