| 发明名称 |
INFLUENZA VIRUS AND TYPE 1 DIABETES |
| 摘要 |
Type 1 diabetes mellitus is characterized by loss of pancreatic insulin-producing beta cells, resulting in insulin deficiency. The usual cause of this beta cell loss is autoimmune destruction. The inventors provide the first evidence of a causal link between influenza virus infection and the development of type 1 diabetes and/or pancreatitis. This causal link between infection and type 1 diabetes and/or pancreatitis provides various therapeutic, prophylactic and diagnostic opportunities. |
| 申请公布号 |
US2015299667(A1) |
申请公布日期 |
2015.10.22 |
| 申请号 |
US201314435016 |
申请日期 |
2013.10.10 |
| 申请人 |
OSPEDALE SAN RAFFAELE S.R.L. ;ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLE VENEZIE |
发明人 |
PIEMONTI Lorenzo;CAPUA Ilaria |
| 分类号 |
C12N7/00;A61K45/06;A61K39/145;A61K31/215;A61K31/351 |
主分类号 |
C12N7/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising an antiviral compound effective against an influenza A virus for use in preventing or treating type 1 diabetes and/or pancreatitis in a patient. |
| 地址 |
Milano IT |
