| 发明名称 |
REJUVENATION OF PRECURSOR CELLS |
| 摘要 |
The present invention relates generally to methods and pharmaceutical compositions for rejuvenating hematopoietic stem cells and progenitor cells from blood, intestinal tissue and dermal tissue by administration of at least one inhibitor of a GT-Pase, such as Cdc42 GTPase. |
| 申请公布号 |
US2015297563(A1) |
申请公布日期 |
2015.10.22 |
| 申请号 |
US201314398386 |
申请日期 |
2013.04.30 |
| 申请人 |
Children's Hospital Medical Center |
发明人 |
Geiger Hartmut;Florian Maria Carolina;Zheng Yi |
| 分类号 |
A61K31/404;A61K35/14 |
主分类号 |
A61K31/404 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for rejuvenating a blood precursor cell, a dermal epithelial precursor cell or an intestinal epithelial precursor cell in a subject comprising: administering to a subject in need of treatment an effective amount of at least one Cdc42-specific inhibitor. |
| 地址 |
Cincinnati OH US |
