WIRELESS INTRACRANIAL MONITORING SYSTEM

摘要

Some embodiments of the present disclosure comprise improved systems and methods for monitoring physiological parameters such as intracranial pressure (“ICP”), intracranial temperature, and subject head position. For example, in some embodiments, an implantable apparatus for measuring ICP can be implanted into a subject skull. The apparatus can comprise an implant body having a hermetically sealed chamber housing a gas at a reference pressure, and a pressure conduction catheter having a proximal end and a distal end, wherein the distal end is configured to extend into the brain through a burr hole in the skull and includes a plurality of ports. A barrier can cover the ports of the distal end of the pressure conduction catheter, wherein the barrier and pressure conduction catheter are filled with a number of gas molecules so that the barrier is not in tension in a predefined range of ICPs.

主权项

1. An implantable apparatus for measuring intracranial pressure (ICP) in a brain housed within a skull, comprising:
a pressure conduction catheter having a proximal end and a distal end, wherein the distal end is configured to extend into the brain through a burr hole in the skull and includes a plurality of ports; a barrier configured to cover the ports of the distal end of the pressure conduction catheter, wherein the barrier and pressure conduction catheter are filled with a predetermined number of gas molecules so that the barrier is not in tension in at least a predefined range of ICPs; a diaphragm coupled to the proximal end of the pressure conduction catheter, the diaphragm configured to deform in response to changes in ICP at the barrier; at least one sensor configured to obtain data indicative of deformation of the diaphragm; and a processor, configured to receive said obtained data and determine the ICP at the barrier based at least in part on the obtained data.