SURFACE MODIFICATION OF POROUS BASE SUPPORTS

摘要

The present invention relates to new separation materials with improved binding capacity, its manufacturing, and application, especially for binding protein A.

主权项

1. Separating materials for affinity chromatography based on hydroxyl-containing porous base supports, to the surfaces of which polymer chains are grafted by covalent bonding, characterised in that
a) two or more grafted polymer chains are initiated from one hydroxyl group on the surface, and b) each polymer chain has multiple derivatizable groups for coupling affinity ligands.