发明名称 |
FUCOIDAN NANOGELS AND METHODS OF THEIR USE AND MANUFACTURE |
摘要 |
Described herein are polymeric drug-carrying nanogels that are capable of targeting to P-selectin for the treatment of cancer and other diseases and conditions associated with P-selectin. Furthermore, in certain embodiments, the nanogels presented here offer a drug release mechanism based on acidic pH in the microenvironment of a tumor, thereby providing improved treatment targeting capability and allowing use of lower drug doses, thereby reducing toxicity. |
申请公布号 |
WO2015161192(A1) |
申请公布日期 |
2015.10.22 |
申请号 |
WO2015US26362 |
申请日期 |
2015.04.17 |
申请人 |
MEMORIAL SLOAN KETTERING CANCER CENTER |
发明人 |
HELLER, DANIEL;SHAMAY, YOSEF |
分类号 |
A61K9/51;A61K31/737;C12P19/56 |
主分类号 |
A61K9/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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