发明名称 |
USE OF [(ARYLOXY)(HETEROARYL)]METHYLPIPERIDINE DERIVATIVES IN MANUFACTURE OF MEDICAMENTS FOR TREATMENT OF DEPRESSION |
摘要 |
The present invention discloses use of a compound represented by formula I, or pharmaceutically acceptable salts thereof in the manufacture of medicaments for the treatment of depression. Specifically it relates to the triple inhibition effect of compounds of formula I on the reuptake of 5-HT, NE and DA. Their antidepressive effects may have broader indications and smaller neurotoxic side effects than single target antidepressants (such as fluoxetine) and dual targets antidepressants (such as duloxetine) currently used in clinic. |
申请公布号 |
WO2015131814(A3) |
申请公布日期 |
2015.10.22 |
申请号 |
WO2015CN73602 |
申请日期 |
2015.03.04 |
申请人 |
NHWA PHARMA. CORPORATION |
发明人 |
GUO, QIANG;ZHAO, SONG;SUN, JIAQUAN;LIU, BIFENG;QIU, YINLI;LI, JUNHONG;PENG, WEIJUAN |
分类号 |
A61K31/4535;A61K31/4525;A61P25/24;C07D405/06;C07D409/06 |
主分类号 |
A61K31/4535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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