Bile acid recycling inhibitors for treatment of Barrett's esophagus and gastroesophageal reflux disease
摘要
<p>Provided herein are methods of treating or ameliorating Barrett's esophagus by administering to an individual in need thereof a therapeutically effective amount of an Apical Sodium-dependent Bile Acid Transporter Inhibitor (ASBTI) or a pharmaceutically acceptable salt thereof. Provided herein are methods of treating or ameliorating gastroesophageal reflux disease (GERD) by administering to an individual in need thereof a therapeutically effective amount of an ASBTI or a pharmaceutically acceptable salt thereof. Also provided are methods for treating or ameliorating symptoms or complications associated with Barrett's esophagus or GERD comprising administering to an individual in need thereof a therapeutically effective amount of ASBTI or a pharmaceutically acceptable salt thereof.</p>
申请公布号
AU2014229050(A1)
申请公布日期
2015.10.22
申请号
AU20140229050
申请日期
2014.03.14
申请人
LUMENA PHARMACEUTICALS, INC
发明人
GEDULIN, BRONISLAVA;GREY, MICHAEL;O'DONNELL, NIALL;KELLER, BRADLEY T.