发明名称 |
ANTIBODIES TO AMYLOID BETA |
摘要 |
Antibody for human amyloid beta. Antibody selectively binds human amyloid beta 42 peptide over human amyloid beta 40 peptide. Antibodies specific for amyloid beta 42 as therapeutic agents for binding amyloid beta 42 peptide and treating conditions associated with amyloidosis, such as Alzheimer's disease. |
申请公布号 |
US2015299299(A1) |
申请公布日期 |
2015.10.22 |
申请号 |
US201314435520 |
申请日期 |
2013.10.15 |
申请人 |
Medlmmune Limited |
发明人 |
Groves Maria;Gustavsson Suzanne;Höglund Kina;Lloyd Chris;Nickson Adrian;Niva Camilla;Simon Sylvia;Lowne David |
分类号 |
C07K16/18 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
1. An isolated antibody molecule that is selective for binding human amyloid beta 1-42 peptide (Aβ1-42) over human amyloid beta 1-40 peptide (Aβ1-40), wherein the antibody molecule is capable of binding soluble monomeric human Aβ1-42 and low n oligomeric (up to pentamer) human Aβ1-42. |
地址 |
Cambridge GB |