发明名称 AXMI-115, AXMI-113, AXMI-005, AXMI-163 AND AXMI-184: INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE
摘要 Compositions and methods for conferring insecticidal activity to host cells are provided. Compositions comprising a coding sequence for a delta-endotoxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in host cells. Compositions also comprise transformed host cells. In particular, isolated delta-endotoxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:4, 5, 6, 13, or 14, or the nucleotide sequence set forth in SEQ ID NO:1, 2, 3, 11, or 12, as well as variants and fragments thereof.
申请公布号 US2015299274(A1) 申请公布日期 2015.10.22
申请号 US201514733552 申请日期 2015.06.08
申请人 Athenix Corporation 发明人 Sampson Kimberly S.;Tomso Daniel J.;Agarwal Shruti;McNulty Brian;Campbell Chris
分类号 C07K14/325;A01N37/18;C12N15/82 主分类号 C07K14/325
代理机构 代理人
主权项 1. A recombinant nucleic acid molecule comprising a nucleotide sequence encoding an insecticidal polypeptide having at least 95% sequence identity SEQ ID NO:14, wherein said nucleotide sequence is operably linked to a heterologous promoter.
地址 Morrisville NC US