| 摘要 |
The present invention relates to prodrugs of monomethyl fumarate (MMF) of formula (I) suitable as a medicament, preferably in the treatment and/or prevention of systemic diseases, autoimmune diseases, inflammatory diseases, for example multiple sclerosis, rheumatoid arthritis and psoriasis. In formula (I) R is hydrogen and n is an integer from 1 to 10, or R is trans -CO-CH=CH-COOCH3 and n is an integer from 2 to 10, or a pharmaceutically acceptable salt, hydrate, solvate, polymorph, and/or mixtures thereof. |
