发明名称 BCR-ABL DIPLOID INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF
摘要 Disclosed are compounds or pharmaceutically acceptable salts thereof having the following general formula: R-Linker-R. The compounds or pharmaceutically acceptable salts thereof provided by the present invention are used as Bcr-Abl diploid inhibitors, which can effectively inhibit the activity of tyrosine kinase, are applicable in treating diseases concerning abnormal activation of such kinases, and have good effects in treating malignant tumors. The method for preparing such inhibitors is simple and convenient, has low cost, and has good application prospects.
申请公布号 WO2015158291(A1) 申请公布日期 2015.10.22
申请号 WO2015CN76804 申请日期 2015.04.16
申请人 CHENGDU UNIVERSITY 发明人 ZHENG, ZHEBIN
分类号 C07D401/14;A61K31/496;A61K31/506;A61P35/00;A61P35/02;C07D215/54;C07D233/64;C07D239/26;C07D403/14;C07D417/14;C07D487/04;C07D519/00 主分类号 C07D401/14
代理机构 代理人
主权项
地址