SENSOR PROBE FOR BIO-SENSING AND CHEMICAL-SENSING APPLICATIONS

摘要

The basic structure and functionality of a probe as disclosed herein allows for flexibly incorporating into the probe, various sensing elements for various sensing applications. Two example applications among these various sensing applications include bio-sensing and chemical-sensing applications. For bio-sensing applications the probe, which is fabricated upon a silicon substrate, includes a bio-sensing element such as a nano-pillar transistor, and for chemical-sensing applications the probe includes a sensing element that has a functionalized contact area whereby the sensing element generates a voltage when exposed to one or more chemicals of interest.

主权项

1. A method comprising:
placing at least a first protruding portion of a probe at a first desired measurement location that provides contact with one of a biological specimen or a chemical specimen; and using a functionalized contact area of a first sensing element mounted on the first protruding portion to sense one of an extracellular field potential or an ionic field potential generated by the one of the biological specimen or the chemical specimen respectively.