发明名称 INKJET GENE PRINTING
摘要 Provided herein are methods and apparatuses for transfecting a cell with a compound of interest by stressing the cell, e.g. with shear stress. The compound of interest may be nucleic acids, proteins, molecules, nanoparticles, drugs, etc., or any combination thereof. Methods of printing cells with an inkjet printing device are also provided, wherein at least a portion of viable cells (preferably at least 1%) are transfected with a compound of interest. Preferably, at least 25% of the cells are viable after printing. In addition, methods of forming an array of viable cells are provided wherein at least a portion of the viable printed cells (preferably at least 1%) are transfected with at least one compound of interest.
申请公布号 US2015299730(A1) 申请公布日期 2015.10.22
申请号 US201514697704 申请日期 2015.04.28
申请人 Wake Forest University Health Sciences 发明人 Xu Tao;Yoo James J.;Atala Anthony
分类号 C12N15/89;A61K31/713 主分类号 C12N15/89
代理机构 代理人
主权项
地址 Winston-Salem NC US