发明名称 |
TARGETED MUTATIONS |
摘要 |
The present invention relates to a process for producing and selecting for targeted mutations in bacterial genomes. In particular, the process relates to the transformation of bacteria with a Recombination Element which comprises the desired mutation followed by homologous recombination of the Recombination Element into the bacterial genome; the CRISPR/Cas system is then used to eliminate bacteria which do not have the desired mutation. |
申请公布号 |
WO2015159087(A1) |
申请公布日期 |
2015.10.22 |
申请号 |
WO2015GB51153 |
申请日期 |
2015.04.16 |
申请人 |
GREEN BIOLOGICS LIMITED |
发明人 |
JENKINSON, ELIZABETH;KRABBEN, PREBEN |
分类号 |
C12N15/10;C12N15/74;C12N15/90 |
主分类号 |
C12N15/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|