发明名称 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS
摘要 The present invention relates to the compound of the formula or pharmaceutically acceptable salts thereof, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, emphysema, and pneumonia.
申请公布号 EP2931712(A1) 申请公布日期 2015.10.21
申请号 EP20130826678 申请日期 2013.12.13
申请人 PARION SCIENCES, INC. 发明人 JOHNSON, MICHAEL, R.
分类号 C07D241/20;A61K31/4965;A61P11/12 主分类号 C07D241/20
代理机构 代理人
主权项
地址