发明名称 |
METHODS OF REDUCING EOSINOPHIL LEVELS |
摘要 |
The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e g, esophagus, stomach, small intestine and colon), or lung. |
申请公布号 |
EP2068927(B1) |
申请公布日期 |
2015.10.21 |
申请号 |
EP20080779619 |
申请日期 |
2008.05.14 |
申请人 |
MEDIMMUNE, LLC;BIOWA, INC. |
发明人 |
KOIKE, MASAMICHI;SPITALNY, GEORGE, L.;WHEELER, ALISTAIR;WHITE, BARBARA |
分类号 |
A61K39/395;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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