| 发明名称 |
METHODS AND COMPOSITIONS FOR INCREASING ARYLSULFATASE A ACTIVITY IN THE CNS |
| 摘要 |
Provided herein are methods and compositions for treating a subject suffering from a deficiency in arylsulfatase A in the CNS. The methods include systemic administration of a bifunctional fusion antibody comprising an antibody to a human insulin receptor and an arylsulfatase A. |
| 申请公布号 |
EP2785378(A4) |
申请公布日期 |
2015.10.21 |
| 申请号 |
EP20120854380 |
申请日期 |
2012.09.10 |
| 申请人 |
ARMAGEN TECHNOLOGIES, INC. |
发明人 |
PARDRIDGE, WILLIAM, M.;BOADO, RUBEN, J. |
| 分类号 |
A61K39/395;A61K39/00;A61P25/00;A61P25/16;A61P25/28;C07K16/28;C12N9/16;C12N9/24;C12N15/62 |
主分类号 |
A61K39/395 |
| 代理机构 |
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代理人 |
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