发明名称 |
Carbon monoxide releasing molecules and uses thereof |
摘要 |
Provided herein are novel carbon-monoxide releasing molecules (CO-RMs) of the Formula (I): and esters, amides, salts, solvates and hydrates thereof; wherein R1 and R2 are as described herein. Also provided are pharmaceutical compositions comprising these compounds, methods of their preparation, and their use in the treatment of liver disease and inflammation.; |
申请公布号 |
US9163044(B2) |
申请公布日期 |
2015.10.20 |
申请号 |
US201214112786 |
申请日期 |
2012.04.19 |
申请人 |
Alfama, Inc. |
发明人 |
Blättler Walter Anton;Romão Carlos J. R. C.;Rodrigues Sandra Sofia Pereira;Kromer Lukas Adrian;Otterbein Leo Edmond;Gallo David John |
分类号 |
A01N55/02;A61K31/28;C07F11/00 |
主分类号 |
A01N55/02 |
代理机构 |
Wolf, Greenfield & Sacks, P.C. |
代理人 |
Wolf, Greenfield & Sacks, P.C. |
主权项 |
1. A compound of Formula:or a salt, ester, amide, solvate, or hydrate thereof, or a combination thereof. |
地址 |
Cambridge MA US |