发明名称 Centrifugal micro-fluidic device and method for detecting analytes from liquid specimen
摘要 A centrifugal micro-fluidic device detecting analytes in a liquid specimen and a method of detection of analytes from a liquid specimen using the micro-fluidic device are provided. Reaction efficiency is increased using a repetitive flow of the liquid specimen induced by an alternating combination of capillary force and centrifugal force, thereby enhancing detection sensitivity.
申请公布号 US9164091(B2) 申请公布日期 2015.10.20
申请号 US201113004933 申请日期 2011.01.12
申请人 SAMSUNG ELECTRONICS CO., LTD. 发明人 Kim In Wook
分类号 G01N33/543;G01N33/558;B01L3/00;G01N35/00 主分类号 G01N33/543
代理机构 Sughrue Mion, PLLC 代理人 Sughrue Mion, PLLC
主权项 1. A centrifugal micro-fluidic device comprising: at least one micro-fluidic structure comprising a chamber and at least one channel connected with the chamber; and a detection unit, wherein the chamber comprises a reaction chamber in which a detectable signal generator is combined with an analyte of a liquid specimen to create a detectable signal generator-analyte complex, and an analysis chamber located downstream from the reaction chamber, wherein the analysis chamber comprises a detection region provided in the form of a strip where a capture binder is combined with the detectable signal generator-analyte complex, and a holder which is directly connected to the reaction chamber through a channel and carries a fluid provided from the reaction chamber, and the holder is disposed between the analysis chamber and a stoppage chamber which receives a portion of the fluid from the analysis chamber after a reaction is completed, wherein the detection region includes one of porous membranes, micro-pore structures and micro-pillars, and wherein the detection region is configured to utilize capillary force to move the fluid to a first end of the analysis chamber and the detection region is configured to utilize centrifugal force to move the fluid to a second end, which is opposite to the first end, of the analysis chamber.
地址 Suwon-si KR